ORIGINAL ARBEITEN

104 ORIGINAL ARBEITEN

1. Largo R.H., Sigg P., Von Felten A., Straub P.W.: Acquired factor IX-inhibitor in a nonhaemophilic patient with autoimmune disease. British Journal of Haematology 26, 129-140 (1974).

2. Largo R.H., Heller V., Straub P.W.: Detection of soluble intermediates of the fibrinogen-fibrin conversion using erythrocytes coated with fibrin monomers. Blood 47, 991-1002 (1976).

3. Largo M.A., Largo R.H.: Visusveränderungen im Verlaufe der Pubertät und Augendominanz im Alter von 10 Jahren. Helvetica Paediatrica Acta 32, 59-69 (1977).

4. Largo R.H., Stützle W.: Longitudinal study of bowel and bladder control by day and at night in the first six years of life. I: Epidemiology and interrelations between bowel and bladder control. Developmental Medicine and Child Neurology 19, 598-606 (1977).

5. Largo R.H., Stützle W.: Longitudinal Study of bowel and bladder control by day and at night in the first six years of life. II: The role of potty training and the child's initiative. Developmental Medicine and Child Neurology 19, 607-613 (1977).

6. Müller U.P., Largo R.H., Straub P.W.: A sensitive latex agglutination method for the detection of soluble fibrin in plasma. Blut 35, 465-479 (1977).

7. Largo R.H., Duc G.: Head growth and changes in head configuration in healthy preterm and term infants during the first six months of life. Helvetica Paediatrica Acta 32, 431-442 (1977).

8. Largo R.H., Gianciaruso M., Prader A.: Die Entwicklung der Darm- und Blasenkontrolle von 0 bis 18 Jahren (Longitudinale Studie). Schweizerische Medizinische Wochenzeitschrift 108, 155-160 (1978).

9. Largo R.H., Stützle W., Gasser Th., Huber J.P., Prader A.: Analysis of the adolescent growth spurt using smoothing spline functions. Annals of Human Biology 5, 421-434 (1978).

10. Largo R.H., Howard J.A.: Developmental progression of play behaviors in children 9 to 30 months of age. I. Spontaneous play and imitation. Developmental Medicine and Child Neurology 21, 299-310 (1979).

11. Largo R.H., Howard J.A.: Developmental progression of play behaviors in children 9 to 30 months of age. II. Spontaneous play and language development. Developmental Medicine and Child Neurology 21, 492 - 503 (1979).

12. Basler K., Largo R.H., Molinari L.: Die Entwicklung des Schlafverhaltens in den ersten fünf Lebensjahren. Helvetica Paediatrica Acta 35, 211-223 (1980).

13. Molinari L., Largo R.H., Prader A.: Analysis of the mid-growth spurt. Helvetica Paediatrica Acta 35, 325-334 (1980).

14. Wälli R., Stettler T., Largo R.H., Fanconi A., Prader A.: Gewicht, Länge und Kopfumfang neugeborener Kinder und ihre Abhängigkeit von kindlichen und mütterlichen Faktoren. Normkurven für das intrauterine Wachstum. Helvetica Paediatrica Acta 35, 397-418 (1980).

15. Largo R.H., Wälli R., Duc G., Fanconi A., Prader A.: Evaluation of perinatal growth. Helvetica Paediatrica Acta 35, 419-436 (1980).

16. Stützle W., Gasser Th., Molinari L., Largo R.H., Prader A., Huber P.J.: Shape-invariant modeling of human growth. Annals of Human Biology 7, 507-528 (1980).

17. Bühler M., Largo R.H.: Aspekte des Schlafverhaltens zwischen 2 und 18 Jahren (Longitudinale Studie). Helvetica Paediatrica Acta 36, 533-541 (1981).

18. Weber M., Largo R.H., Duc G.: Psychomotorische und neurologische Entwicklung frühgeborener Kinder unter versus über 1500g Geburtsgewicht. In: Huch A.,R., Duc G., Roth G.: Klinisches Management der kleinen Frühgeborenen. Thieme, Stuttgart. 26-28 (1982).

19. Largo R.H., Prader A.: Pubertal development in Swiss boys. Helvetica Paediatrica Acta 38, 211-228 (1983).

20. Largo R.H., Prader A.: Pubertal development in Swiss girls. Helvetica Paediatrica Acta 38, 229-243 (1983).

21. Molinari L., Largo R.H., Prader A.: Target height and secular trend in the Swiss population. In: Borms J., Hauspie R., Sand A., Susanne C., Hebbelinck M.: Human Growth and Development.193-200 (1984).

22. Largo R.H., Hunziker H.A.: A developmental approach in the manage¬ment of children with sleep disturbances in the first three years of life. European Journal of Pediatrics 142, 170-173 (1984).

23. Gasser T., Köhler W., Kneip A., Largo R.H., Molinari L., Prader A.: Velocity and acceleration of height growth using Kernel estimation. Annals of Human Biology 11, 397-411 (1984).

24. Flug D., Largo R.H., Prader A.: Menstrual patterns in adolescent Swiss girls. Annals of Human Biology 6, 495-508 (1984).

25. Flug D., Largo R.H., Prader A.: Symptoms related to menstruation in Swiss adolescent girls. A longitudinal study. Annals of Human Biology 12, 161-168 (1985).

26. Largo R.H., Schinzel A.: Developmental and behavioral disturbances in 13 boys with Fragile-X-Syndrome. European Journal of Pediatrics 143, 269-275 (1985).

27. Largo R.H., Weber M., Comenale-Pinto L., Duc G.: Early development of locomotion: Significance of prematurity, cerebral palsy and sex. Developmental Medicine and Child Neurology 27, 183-191 (1985).

28. Schinzel A., Largo R.H.: The Fragile-X-Syndrome. Clinical and cytogenetic findings in 16 prepubertal boys and their 5 families. Helvetica Paediatrica Acta 40, 133-152 (1985).

29. Gasser T., Köhler W., Kneip A., Largo R.H., Molinari L., Prader A.: An analysis of the mid-growth and adolescent spurt of height based on acceleration. Annals of Human Biology 12, 129-148 (1985).

30. Gasser T., Köhler W., Müller H.G., Largo R.H., Molinari L., Prader A.: Human height growth: Correlational and multi-variate structure of velocity and acceleration. Annals of Human Biology 12, 501-515 (1985).

31. Hunziker H.A., Largo R.H., Zachmann M., Prader A.: "Catch down growth" pattern in patients with congenital adrenal hyperplasia and delayed initiation of therapy. European Journal of Pediatrics 144, 550-553 (1986).

32. Largo R.H., Comenale Pinto L., Weber M., Molinari L., Duc G.: Language development of term and preterm children during the first five years of life. Developmental Medicine and Child Neurology 28, 333-350 (1986).

33. Hunziker U., Largo R.H.: Betreuung von Risikokindern: Eltern-Kind-Beziehung im ersten Lebenshalbjahr (Eine deskriptive Studie). Monatsschrift für Kinderheilkunde 134, 246-252 (1986).

34. Illig R., Largo R.H., Weber M., Augsburger Th., Lipp A., Wissler D., Perrenoud A.E., Torresani T.: Sixty children with congenital hypo- thyroidism detected by neonatal thyroid screening: Mental development at 1, 4 and 7 years: A longitudinal study. Acta Endocrinologica, Supplementum 279, 346-353 (1986).

35. Duc G., Largo R.H.: Anterior fontanel: Normal size and closure in term and preterm infants. Pediatrics 78, 904-908 (1986).

36. Largo R.H.: Der praktizierende Kinderarzt am Scheideweg? Helvetica Paediatrica Acta, Supplementum 51, 5-14 (1986).

37. Kessler R., Largo R.H.: Prospektive Studie über die Tätigkeit des praktizierenden Kinderarztes. I. Praxisorganisation und sozioökonomische Daten. Helvetica Paediatrica Acta, Supplementum 51, 15-28 (1986).

38. Diethelm M., Largo R.H.: Prospektive Studie über die Tätigkeit des praktizierenden Kinderarztes. II. Besuchsgründe und Diagnosen. Helvetica Paediatrica Acta, Supplementum 51, 29-52 (1986).

39. Suter F.E., Largo R.H.: Prospektive Studie über die Tätigkeit des praktizierenden Kinderarztes. III. Abklärungen, Behandlungen und Ueberweisungen. Helvetica Paediatrica Acta, Supplementum 51, 53-66 (1986).

40. Schmid M., Largo R.H.: Visual acuity and stereopsis between 5 and 10 years (A cross-sectional study). European Journal of Pediatrics 145, 475-479 (1986).

41. de Perrot A.C., Largo R.H., Schneider Ph.: Die Erziehungsberaterin in der kinderärztlichen Praxis. Eine prospektive Studie über die Zusammenarbeit von Erziehungsberaterin und Kinderarzt. Pro Juventute, Zürich (1987).

42. A Illig R., Largo R.H., Qin Qing, Torresani T., Rocchiccioli P., Larsson A.: Mental development in congenital hypothyroidism after introduction of neonatal screening (European Collaborative Study). Archives of Disease in Childhood 62, 1050-1055 (1987).

42. B Illig R., Largo R.H., Qin Qing, Torresani T., Rocchiccioli P.: Etude collaborative européenne sur l'hypothyroidie congénitale. Archives Françaises de Pédiatrie 44, 715-20 (1987).

42. C Illig R., Largo R.H., Qin Qing, Torresani T., Rocchiccioli R., Giovannelli G.: Studio Collaborativo europeo sull' ipotiroidismo congenito. Rivita Italiana di Pediatria 13, 8-16 (1987).

42. D Illig R., Largo R.H., Qin Qing, Torresani T., Rocchiccioli R., Klett P.: Geistige Entwicklung bei angeborenen Hypothyreosen. Deutsche Medizinische Wochenschrift 113, 667-671 (1988).

43. Largo R.H., Prader A.: Pubertal development in girls: variability and interrelationsships. Pediatrician 14, 212-218 (1987).

44. Hunziker U.A., Largo R.H., Duc G.: Neonatal metatarsus adductus, joint mobility, axis and rotation of the lower extremity in term and preterm children at five years of age. European Journal of Pediatrics 148, 19-23 (1988).

45. Prader A., Largo R.H., Molinari L., Issler C.: Physical growth of Swiss children from birth to 20 years of age (First Zurich Longitudinal Study of Growth and Development). Helvetica Paediatrica Acta, Supplementum 52 (1989).

46. Largo R.H., Pfister D., Molinari L., Kundu S., Lipp A., Duc G.: Significance of prenatal, perinatal and postnatal factors in the development of AGA-preterm children at 5-7 years. Developmental Medicine and Child Neurology 31, 440-456 (1989).

47. Gasser T., Kneip A., Binding A., Largo R.H., Prader A., Molinari L.: Flexible methods for nonparametric fitting of individual and sample growth curves. In: Tanner J.M.: Auxology 88. Smith Gordon, London (1989).

48. Largo R.H., Graf S., Kundu S., Hunziker U., Molinari L.: Predicting developmental outcome at school age from infant tests in normal, at risk and retarded children. Developmental Medicine and Child Neurology 32, 30-45 (1990).

49. Schaefer F., Seidel C., Binding A., Gasser T., Largo R.H., Prader A., Schärer K.: Pubertal growth in chronic renal failure. Pediatric Research 28, 5-10 (1990).

50. Steinlin M., Martin E., Largo R., Bösch C., Boltshauser E.: Congenital ocular motor apraxia: A neurodevelopmental and neuroradiological study. Journal of Neuro-Ophthalmology 10, 27-32 (1990).

51. Largo R.H., Molinari L., Kundu S., Hunziker U., Duc G.: Neurological outcome at schoolage of high risk AGA-preterm children. European Journal of Pediatrics 149, 835-844 (1990).

52. Largo R.H., Molinari L., Kundu S., Lipp A., Duc G.: Intellectual outcome, speech and school performance in high risk AGA-preterm child¬ren. European Journal of Pediatrics 149, 845-850 (1990).

53. Gasser T., Kneip A., Ziegler P., Largo R., Prader A.: A method for determining the dynamics and intensity of average growth. Annals of Human Biology 17, 459-474 (1990).

54. Largo R.H., Etter K., Bucher H.U., Duc G.: Developmental outcome at age 2 of preterm infants less than 1250 grams at birth. In: Duc G., Huch A., Huch R.: The Very Low Birthweight Infant. Thieme, Stuttgart. 84-87 (1990).

55. Bucher H.U., Biedermann K., Mieth D., Etter K., Largo R.H.: Association between perinatal factors and cerebral outcome two years after term. In: Duc G., Huch A., Huch R.: The Very Low Birthweight Infant. Thieme, Stuttgart. 68-70 (1990).

56. Thun-Hohenstein L., Largo R.H., Kundu S.: Early fine motor and adaptive development in term and high risk AGA-preterm children. European Journal of Pediatrics 150, 562-569 (1991).

57. Steinlin M., Dirr R., Martin E., Bösch C., Largo R.H., Fanconi S., Bolthauser E.: MRI following severe perinatal asphyxia: Preliminary experience. Pediatric Neurology 7, 164-170 (1991).

58. Gasser T., Kneip A., Binding A., Prader A., Largo R.H., Molinari L.: The dynamics of linear growth in distance, velocity and acceleration. Annals of Human Biology 18, 187-205 (1991).

59. Gasser T., Kneip A., Ziegler P., Largo R.H., Molinari L., Prader A.: The dynamics of growth of width in distance, velocity and acceleration. Annals of Human Biology 18, 449-461 (1991).

60. Steinlin M., Zürrer M., Martin E., Boesch Ch., Largo R.H., Boltshauser E.: Magnet resonance imaging in microcephalic children. Neuropediatrics 22, 184-189 (1991).

61. Largo R.H., Riederer M., Molinari L., Hunziker U., Duc G.: Repetitive, alternierende und sequentielle Bewegungsabfolgen im Alter von 7 bis 10 Jahren bei termin- und frühgeborenen Kindern. In: Lütschg J.: Aktuelle Neuropädiatrie. Berlin, Springer. 92-97 (1991).

62. Neuhaus Th., Smaadahl F., Lose M., Largo R.H.: Neue Gesichter und alte Krankheiten: Grenzsanitarische Untersuchungen bei Asylbewerber-kindern 1990-1991. Schweizerische Medizinische Wochenschrift 122, 1838-1842 (1992).

63. Largo R.H., Kundu S., Thun-Hohenstein L.: Early motor development in term and preterm children. In: Kalverboer A.F., Hopkins B., Geuze R.H.: Motor Development in Early and Later Childhood: Longitudinal Approaches. Cambridge University Press, Cambridge. 247-265 (1993).

64. Gasser Th., Ziegler P., Kneip A., Prader A., Molinari L., Largo R.: The dynamics of growth of weight, circumferences and skinfolds in distance, velocity and acceleration. Annals of Human Biology 20, 239-259 (1993).

65. Baenziger O., Martin E., Steinlin M., Good M., Largo R., Burger R., Fanconi S., Duc G., Buchli R., Rumpel H., Boltshauser E.: Early pattern recognition in severe perinatal asphyxia: a prospective MRI study. Neuroradiology 35, 437-442 (1993).

66. A Ohrt B., Schlack H.-G., Largo R.H., Michaelis R., Neuhäuser G.: Erfassen von Entwicklungsauffälligkeiten bei Fünfjährigen. Ein normierter Fragebogen. pädiatrische praxis 46, 11-19 (1993).

66. B Ohrt B., Schlack H.-G., Largo R.H., Michaelis R., Neuhäuser G.: Erfassen von Entwicklungsauffälligkeiten bei Fünfjährigen. Ein normierter Fragebogen. In: Schlack H.G., Largo R.H., Michaelis R., Neuhäuser G., Ohrt B.: Praktische Entwicklungsneurologie. Hans Marseille, Wien. 153-160 (1994).

67. Steinlin M., Good M., Martin E., Bänziger O., Largo R.H., Boltshauser E.: Congenital Hemiplegia: Morphology of cerebral lesions and pathogenetic aspects from MRI. Neuropediatrics 24, 224-229 (1993).

68. Gasser Th., Ziegler P., Seifert B., Prader A., Molinari L., Largo R.H.: Measures of body mass and of obesity from infancy to adulthood and their appropriate transformation. Annals of Human Biology 21, 111-125 (1994).

69. Gasser Th., Kneip A., Ziegler P., Molinari L., Prader A., Largo R.H.: Development and outcome of indices of obesity in normal children. Annals of Human Biology 21, 275-286 (1994).

70. Gasser Th., Ziegler P., Largo R.H., Molinari L., Prader A.: A Longitudinal study of lean and fat area at the arm. Annals of Human Biology 21, 303-314 (1994).

71. Künzle Ch., Bänziger O., Martin E., Thun-Hohenstein L., Steinlin M., Good M., Fanconi S., Boltshauser E., Largo R.H.: Prognostic value of early MR imaging in term infants with severe perinatal asphyxia. Neuropediatrics 25, 191-200 (1994).

72. Molinari L., Gasser T., Largo R.H., Prader A.: Child-adult correlations for anthropometric measurements. In: Hauspie R., Lindgren G., Falkner F.: Essays on Auxology. Mead Castle, London. 164-177 (1995).

73. Gasser T., Ziegler P., Burkhardt S., Molinari L., Largo R.H., Prader A.: Prediction of adult skinfolds and body mass from infancy through adolescence. Annals of Human Biology 22, 3, 217-233 (1995).

74. Martin E., Buchli R., Ritter S., Schmid R., Largo R.H., Boltshauser E., Fanconi S., Duc G., Rumpel H.: Diagnostic and Prognostic Value of Cerebral 31P Magnetic Resonance Spectroscopy in Neonates with Perinatal Asphyxia. Pediatric Research 40, 5, 749-758 (1996).

75. Largo R.H., Molinari L., von Siebenthal K., Wolfensberger U.: Does a profound change in toilet-training affect development of bowel and bladder control? Developmental Medicine and Child Neurology 38, 106-116 (1996).

76. Largo R.H., von Siebenthal K., Etter K., Morales C., Bucher H.U., Molinari L., Duc G.: Body proportionality in growth-retarded VLBW infants. Journal of Perinatal Medicine 25, 17-25 (1997).

77. Kakebeeke T.H., von Siebenthal K., Largo R.H.: Differences in movement quality at term among preterm and term infants. Biology of the Neonate, 71, 367-378 (1997).

78. Schinzel A., Binkert F., Brecevic L., Dutly F., Largo R.H.: Multiple congenital anomalies including the Rieger eye malformation in a boy with interstitial deletion of (4)(q25 –> q27) secondary to a balanced insertion in his normal father: evidence for haplotype insufficiency causing the Rieger malformation. Journal of Medical Genetics 34, 1012-1014 (1997).

79. Kakebeeke T.H., von Siebenthal K., Largo R.H.: Movement quality in preterm infants prior to term. Biology of the Neonate, 73, 145-154 (1998).

80. Strebel Caflisch R., Bucher H.U., Dal Santo B., Fawer C.L., von Siebenthal K., Largo R.H.: Ophthalmologische Störungen bei ehemals extrem kleinen Frühgeborenen im Alter von 10 Jahren: Eine Erhebung der Jahrgänge 1983-1985 in der ganzen Schweiz. Monatsschrift für Kinderheilkunde, 146, 230-234 (1998).

81. Neuhaus T.J., Ritter S., Largo R.H.: Bladder control a consequence of maturation: evidence after renal transplantation. Developmental Medicine and Child Neurology, 40, 193-194 (1998).

82. Eiholzer U., Bodmer P., Bühler M., Döhmann U., Meyer G., Reinhard P., Schimert G., Varga G., Wälli R., Largo R.H., Molinari L.: Longitudinal monthly body measurements from 1 to 12 months of age. A study by practitioners for practitioners. European Journal of Pediatrics, 157, 547-552 (1998).

83. Largo R.H., Molinari L., von Siebenthal K., Wolfensberger U.: Development of bladder and bowel control: Significance of prematurity, perinatal risk factors, psychomotor development and gender. European Journal of Pediatrics, 158, 115-122 (1999).

84. Sheehy A., Gasser T., Molinari L., Largo R.H.: An analysis of variance of the pubertal and midgrowth spurts for length and width. Annals of Human Biology, 26, 4, 309-331 (1999).

85. Achermann S., Largo R.H., Kotzot D., Riegel M., Schinzel A.: Short stature, myopia, severe developmental delay, and peculiar facial appearance in two brothers: A new syndrome? American Journal of Medical Genetics 86, 486-491 (1999).

86. Gasser T., Sheehy A., Molinari L., Largo R.H.: Sex Dimorphism in Growth. Annals of Human Biology 27, 187-197 (2000).

87. Malich S., Largo R.H., Schinzel A., Molinari L., Eiholzer U.: Phenotypic heterogeneity of growth and psychometric intelligence in Prader-Willi syndrome: Variable expression of a contiguous gene syndrome or parent-child resemblance? American Journal of Human Genetics, 91, 298-304 (2000).

88. Sheehy A., Gasser T., Molinari L., Largo R.H.: Contribution of growth phases to adult size. Annals of Human Biology, 27, 281-298 (2000).

89. Hermanussen M., Largo R.H., Molinari L.: Canalisation in human growth: a widely accepted concept reconsidered. European Journal of Pediatrics, 160, 163-167 (2001).

90. Gasser T., Sheehy A., Molinari L., Largo R.H.: Growth processes leading to a large or small adult size. Annals of Human Biology, 28, 3, 319-327 (2001).

91. Gasser T., Sheehy A., Largo R.H.: Statistical characterization of the pubertal growth spurt. Annals of Human Biology, 28, 4, 395-402 (2001).

92. Largo R.H., Caflisch J.A., Hug F., Muggli K., Molnar A., Molinari L., Sheehy A., Gasser T.: Neuromotor development from 5 to 18 years: Part 1: Timed performance. Developmental Medicine and Child Neurology, 43, 436-443 (2001).

93. Largo R.H., Caflisch J.A., Hug F., Muggli K., Molnar A., Molinari L.: Neuromotor development from 5 to 18 years: Part 2: Associated movements. Developmental Medicine and Child Neurology, 43, 444-453 (2001).

94. Gasser T., Sheehy A., Molinari L., Largo R.H.: Growth of early and late maturers. Annals of Human Biology, 28, 3, 328-336 (2001).

95. Schönle E., Schönle D., Molinari L., Largo R.H.: Impaired intellectual development in children with Type 1 diabetes: association with HbA1c, age at diagnosis and sex. Diabetologia 45, 108-114 (2002).

96. Sheehy A., Gasser T., Largo R.H., Molinari L.: Short-term and long-term variability of standard deviation scores for size in children. Annals of Human Biology 29, 2, 202-218 (2002).

97. A Largo R.H., Fischer J.E., Caflisch J.A.: Zürcher Neuromotorik. AWE Verlag, Zürich (2002).

97. B Largo R.H., Fischer J.E., Caflisch J.A.: Zurich Neuromotoro Assessment. AWE Verlag, Zurich (2002).

98. Iglowstein I., Jenni O.G., Molinari L., Largo R.H.: Sleep duration from infancy to adolescence: Reference values and generational trends. Pediatrics, 11, 302-307 (2003).

99. Latal B., von Siebenthal K., Kovari H., Bucher H.U., Largo R.H.: Postnatal growth in VLBW infants: significant association with neurodevelopmental outcome. Journal of Pediatrics, 143, 163-170 (2003).

100. Zankl A., Brooks D., Boltshauser E., Largo R.H., Schinzel A.: Natural history of twin disruption sequence. American Journal of Medical Genetics, 127A, 133-138 (2004).

101. Jenni O.G., Zinggeler Fuhrer H., Iglowstein I., Molinari L., Largo R.H.: A longitudinal study of bedsharing and sleep problems among swiss children in the first 10 years of life. Pediatrics 115, 233-240 (2005).

102. Molinari L., Gasser T., Largo R.H.: TW3 bone age: RUS/CB and gender differences of percentiles for score and score increments. Annals of Human Biology, 31, 4, 421-435 (2004).

103. Latal B., Braun C., von Siebenthal K., Bucher H.U., Largo R.H.: Improved Outcome for Very Low Birth Weight Multiple Births. Pediatric Neurology 32, 2, 87-93 (2005).

104. Martin E., Keller M., Ritter S., Largo R.H., Thiel T., Loenneker T.: Contribution of Proton Magnetic Resonance Spectroscopy to the Evaluation of Children with Unexplained Developmental Delay. Pediatric Research, 58, 4, 754-760 (2005).